Just Get More Fiber!
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Διαπίστωσαν ότι ένα στέλεχος βακτηρίων, που ονομάζεται Lawsonibacter asaccharolyticus (L. asaccharolyticus), συνδέθηκε έντονα με την κατανάλωση καφέ.
https://www.oloygeia.gr/diatrofi/poso-kafe-gia-kala-vaktiria-entero/
Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts.
https://www.nature.com/articles/s41564-024-01858-9
https://www.oloygeia.gr/diatrofi/poso-kafe-gia-kala-vaktiria-entero/
Coffee consumption is associated with intestinal Lawsonibacter asaccharolyticus abundance and prevalence across multiple cohorts.
https://www.nature.com/articles/s41564-024-01858-9
Fennel Seeds
Chewing fennel seeds is considered beneficial for gut health, have been traditionally used in various cultures for their digestive properties. They may help alleviate bloating, gas, and indigestion. The seeds contain a compound called anethole that can relax the muscles in the gastrointestinal tract, which may aid in digestion. Additionally, fennel seeds have antioxidant and anti-inflammatory properties, which can contribute to overall gut health.
use : chew (5 to 10 minutes) the seeds before or after meals.
tested&working
reference :
CCF Tea
Chewing fennel seeds is considered beneficial for gut health, have been traditionally used in various cultures for their digestive properties. They may help alleviate bloating, gas, and indigestion. The seeds contain a compound called anethole that can relax the muscles in the gastrointestinal tract, which may aid in digestion. Additionally, fennel seeds have antioxidant and anti-inflammatory properties, which can contribute to overall gut health.
use : chew (5 to 10 minutes) the seeds before or after meals.
tested&working
reference :
CCF Tea
(2025) Clinical trial - novel nutritional formula treats gut microbial overgrowth
https://medicalxpress.com/news/2025-04-clinical-trial-nutritional-formula-effectively.html [2]
https://mbiota.com/
Mastiha Oil for Crohn Disease, IBS
https://www.pipiscrew.com/threads/fresh-oregano-tea-benefits.151309/post-150418
https://medicalxpress.com/news/2025-04-clinical-trial-nutritional-formula-effectively.html [2]
https://mbiota.com/
Mastiha Oil for Crohn Disease, IBS
https://www.pipiscrew.com/threads/fresh-oregano-tea-benefits.151309/post-150418
metabolic endotoxemia
= the lipopolysaccharides (aka LPS or else Endotoxins) found in the bacteria cell wall, that (gut) bacteria generate, fall in blood stream (due leaky gut).
sdLDL = doing the atherosclerosis. sdLDL easily oxidized. Going into endothelium of blood vessels and made the atherosclerosis.
the lipopolysaccharides bind to LDL and make it sdLDL (here is possible your LDL count to be OK, but sdLDL not)
sdLDL associated with fatty liver which associated with gut problems.
Stress increasing the lipopolysaccharides to your bloodstream ( description above^ ) even when you dont have gut problems, for moment/hours can make it leaky gut. Here is how @ the brain communicates via vagal nerve with the gut and orders to release cortisol hormone and this releases also peptides from mastcells then the gut lining destroyed (inflammation & permeability).
Eating junk food also helps lipopolysaccharides penetrate the gut.
Bad bacteria lipopolysaccharides penetrate the gut.
70% of immune system is in the gut, T cells and B cells exist there, LPS when passing to bloodstream stimulate those cells and resulting to produce inflammatory cytokines molecules (inflammation), cause immune problem as well.
Inflammatory cytokines molecules travel to the brain, passing the BBB and causes inflammation in the brain (mental fog / depression). Depression associated with atherosclerosis.
LSP goes to the liver and cause fatty liver [2] and the muscles made insulin resistant. You get a metabolic syndrome,
All those markers are of atherosclerosis. The metabolic syndrome causes inflammatory fat, the LPS going into the healthy fat tissues, activates again the immune system, that's why we found inflammatory cells in the fat (obesity person : almost the 50% of the fat are inflammatory molecules).
source (Dr. Pradip Jamnadas)
ref - 2024 - Metabolic Endotoxemia - From the Gut to Neurodegeneration
(JUL/2025) imidazole propionate molecule produced by gut bacteria causes atherosclerosis
GPT :
LDL-C (Low-Density Lipoprotein Cholesterol) : Refers to the total cholesterol content within all LDL particles in the bloodstream. It is a common measure used in lipid panels to assess cardiovascular risk. Includes all sizes of LDL particles, both large and small, and is typically measured in milligrams per deciliter (mg/dL).
sdLDL (Small Dense LDL) : Refers to a subclass of LDL particles that are smaller and denser than typical LDL particles. These particles are often considered more atherogenic (more likely to promote the formation of fatty plaques in arteries) than larger, less dense LDL particles. Elevated levels of sdLDL are associated with a higher risk of cardiovascular events, even when total LDL-C levels are within normal ranges.
= the lipopolysaccharides (aka LPS or else Endotoxins) found in the bacteria cell wall, that (gut) bacteria generate, fall in blood stream (due leaky gut).
sdLDL = doing the atherosclerosis. sdLDL easily oxidized. Going into endothelium of blood vessels and made the atherosclerosis.
the lipopolysaccharides bind to LDL and make it sdLDL (here is possible your LDL count to be OK, but sdLDL not)
sdLDL associated with fatty liver which associated with gut problems.
Stress increasing the lipopolysaccharides to your bloodstream ( description above^ ) even when you dont have gut problems, for moment/hours can make it leaky gut. Here is how @ the brain communicates via vagal nerve with the gut and orders to release cortisol hormone and this releases also peptides from mastcells then the gut lining destroyed (inflammation & permeability).
Eating junk food also helps lipopolysaccharides penetrate the gut.
Bad bacteria lipopolysaccharides penetrate the gut.
70% of immune system is in the gut, T cells and B cells exist there, LPS when passing to bloodstream stimulate those cells and resulting to produce inflammatory cytokines molecules (inflammation), cause immune problem as well.
Inflammatory cytokines molecules travel to the brain, passing the BBB and causes inflammation in the brain (mental fog / depression). Depression associated with atherosclerosis.
LSP goes to the liver and cause fatty liver [2] and the muscles made insulin resistant. You get a metabolic syndrome,
- blood sugar goes up
- triglycerides go up
- HDL goes down
All those markers are of atherosclerosis. The metabolic syndrome causes inflammatory fat, the LPS going into the healthy fat tissues, activates again the immune system, that's why we found inflammatory cells in the fat (obesity person : almost the 50% of the fat are inflammatory molecules).
source (Dr. Pradip Jamnadas)
ref - 2024 - Metabolic Endotoxemia - From the Gut to Neurodegeneration
(JUL/2025) imidazole propionate molecule produced by gut bacteria causes atherosclerosis
GPT :
LDL-C (Low-Density Lipoprotein Cholesterol) : Refers to the total cholesterol content within all LDL particles in the bloodstream. It is a common measure used in lipid panels to assess cardiovascular risk. Includes all sizes of LDL particles, both large and small, and is typically measured in milligrams per deciliter (mg/dL).
sdLDL (Small Dense LDL) : Refers to a subclass of LDL particles that are smaller and denser than typical LDL particles. These particles are often considered more atherogenic (more likely to promote the formation of fatty plaques in arteries) than larger, less dense LDL particles. Elevated levels of sdLDL are associated with a higher risk of cardiovascular events, even when total LDL-C levels are within normal ranges.
| Examination | 22/JAN | 05/MAY | Range |
|---|---|---|---|
| Ουρία (Urea) | 47 mg/dl | 27 mg/dl | 10 - 50 |
| Κρεατινίνη (Creatinine) | 1.15 mg/dl | 1.08 mg/dl | 0.6 - 1.3 |
| Σίδηρος (Iron) | 65.2 μg/dl | 88.8 μg/dl | 33 - 193 |
| Φερριτίνη (Ferritin) | 125.0 ng/ml | 163 ng/ml | 30 - 400 |
| Παραθορμόνη (Parathormone) | 35.8 pg/ml | 35.9 pg/ml | 15 -65 |
| Ινσουλίνη (Insulin) | 2.64 μU/ml | 2.79 μU/ml | 2.6 - 24.9 |
| Vitamin B12 | 264.0 pg/ml | 620 pg/ml | 197-771 |
| Φυλλικό οξύ (Folic acid) | 4.0 ng/ml | 15.4 ng/ml | 3.89 - 26.8 |
| Vitamin D (OH form) | 43.30 ng/ml | 93.6 ng/ml | 30 - 100 |
03/OCT - appointment to holistic, suggested for 3 months
| Supplement | as | Dose | RDA |
|---|---|---|---|
| Solgar Folate 400mcg | Metafolin | 1 pill at breakfast | 400mcg |
| Solgar B-12 Nuggets 1000mcg | Methylcobalamin | 1 nugget at breakfast | 2.4mcg |
| Now Foods Vitamin D-3 10000IU | Cholecalciferol from Lanolin | 1 pill at meal | 600IU or 15 mcg |
| Doctor Formulas Vitamin K2 200mcg | Menaquinone-7 | 1 pill at meal | 120mcg |
| Solgar Chelated Magnesium 400mg | glycinate chelate, oxide | 1 pill at meal | 420mg |
| Life Extension Vitamin C & Quercetin 1000mg | Ascorbic acid | 1 pill at breakfast + 1 pill at meal | 90mg |
| (optional) Vivomixx neo 9 | 1 sachet per day (fast for 1 hour before and after consuming) best working, stop eat for the day 18:00, take it 20:00 |
12/MAY - appointment to holistic, suggested take for ever a custom multivitamin (no branded)
| Ingredients / 2 caps: |
|---|
| Ester-C (Calcium Ascorbate) – 700 mg |
| Vitamin D3 – 7000 IU |
| Vitamin K2 VITAL – 140 µg |
| Magnesium (Bisglycinate Chelate) – 280 mg |
| Zinc (Zinc Bisglycinate) – 20 mg |
| B1 Thiamine – 70 mg |
| B2 Riboflavin Phosphate – 70 mg |
| B3 Nicotinamide – 70 mg |
| B5 Pantothenate – 70 mg |
| Biotin – 700 µg |
| Methyl B6 (Pyridoxal 5-Phosphate) – 70 mg |
| Methyl B12 – 700 µg |
| Folate Quatrefolic – 550 µg |
| Choline – 70 mg |
| Inositol – 70 mg |
| Copper Citrate – 1.5 mg |
| Chromium Picolinate – 70 µg |
| Selenium (L-selenomethionine) – 150 µg |
GPT:
The sensitivity of an individual's digestive system can vary widely due to several factors, and this can influence how they react to freshly cooked versus reheated food. Here are some key points to consider:
Διαλυτές ίνες (Soluble Fiber) : Αυτός ο τύπος ινών διαλύεται στο νερό και μπορεί να βοηθήσει στη μείωση των επιπέδων χοληστερόλης στο αίμα και στη σταθεροποίηση των επιπέδων σακχάρου στο αίμα. Μπορεί επίσης να προάγει το αίσθημα πληρότητας, το οποίο μπορεί να βοηθήσει στη διαχείριση του βάρους. Είναι η τροφή για τα καλά βακτήρια, όλα τα πρεβιοτικά ανήκουν εδώ.
Αδιάλυτες φυτικές ίνες (Insoluble Fiber) : Αυτό το είδος δεν διαλύεται στο νερό και είναι σημαντικό για την υγεία του πεπτικού συστήματος. Προσθέτει όγκο στα κόπρανα και βοηθάει την τροφή να περάσει πιο γρήγορα από το πεπτικό σύστημα, γεγονός που μπορεί να αποτρέψει τη δυσκοιλιότητα.
The sensitivity of an individual's digestive system can vary widely due to several factors, and this can influence how they react to freshly cooked versus reheated food. Here are some key points to consider:
1. Digestive Enzyme Activity
- Freshly Cooked Food: When food is freshly cooked, it may retain more moisture and heat, which can affect how enzymes in the digestive system break it down. Some people may find that their digestive enzymes are less effective at processing certain foods when they are hot and fresh.
- Reheated Food: Reheating food can change its texture and temperature, potentially making it easier for some individuals to digest. The cooling process may also allow for some breakdown of complex carbohydrates, making them easier to digest upon reheating.
2. Food Structure Changes
- Cooking alters the physical structure of food. For example, pressure cooking can break down cell walls and make food softer. However, this can also lead to a higher concentration of certain compounds that may be harder for some people to digest.
- When food is cooled and then reheated, the structure may change again, potentially making it easier for the body to process.
Διαλυτές ίνες (Soluble Fiber) : Αυτός ο τύπος ινών διαλύεται στο νερό και μπορεί να βοηθήσει στη μείωση των επιπέδων χοληστερόλης στο αίμα και στη σταθεροποίηση των επιπέδων σακχάρου στο αίμα. Μπορεί επίσης να προάγει το αίσθημα πληρότητας, το οποίο μπορεί να βοηθήσει στη διαχείριση του βάρους. Είναι η τροφή για τα καλά βακτήρια, όλα τα πρεβιοτικά ανήκουν εδώ.
Αδιάλυτες φυτικές ίνες (Insoluble Fiber) : Αυτό το είδος δεν διαλύεται στο νερό και είναι σημαντικό για την υγεία του πεπτικού συστήματος. Προσθέτει όγκο στα κόπρανα και βοηθάει την τροφή να περάσει πιο γρήγορα από το πεπτικό σύστημα, γεγονός που μπορεί να αποτρέψει τη δυσκοιλιότητα.
| Product | Soluble Fiber Types | Insoluble Fiber Types |
|---|---|---|
| Glucomannan, Mucilage, Psyllium | Cellulose, Hemicellulose | |
| Hemp | Gums, Mucilage | Cellulose, Lignin |
| Buckwheat | Beta-glucans, Fructooligosaccharides, Pectins | Cellulose |
| Flaxseeds | Mucilage, Lignans | Cellulose |
| Quinoa | Beta-glucans, Fructooligosaccharides, Pectins | Cellulose |
| Mung Bean Sprouts | Pectins, Gums, Fructooligosaccharides | Cellulose |
Betaine HCl Hydrochloric Acid w/ Pepsin
It features Pepsin an enzyme that helps digest proteins, plus betaine hydrochloride to promote proper pH levels in the stomach. Together they make an excellent digestive team to help tackle protein problems.
Swanson w/ VegPeptase (iHerb)
Lamberts w/ Pepsin
reddit
Stay on suggested use (max 2 capsules), huge doses of Betaine conflicts with Methylation.
Functions of Betaine HCl
Pepsin is an enzyme that plays a crucial role in the digestion of proteins. It is produced in the stomach of animals, including humans.
VegPeptase (a vegan-sourced pepsin) an enzyme that helps digest proteins.
VegPeptase is not extracted from fruits, instead, it is primarily produced through fermentation using certain strains of fungi or bacteria. While many enzymes can be extracted from fruits, VegPeptase specifically does not originate from this source.
Fruits may contain natural enzymes, such as bromelain from pineapples or papain from papayas, but VegPeptase derives from plant-based microbial processes rather than direct extraction from fruits.
Enzymes are specialized types of proteins that act as biological catalysts, speeding up chemical reactions in the body. While all enzymes are proteins, not all proteins are enzymes. Proteins serve a broader range of functions, including structural support, transport, and immune responses.
Biological catalysts are substances that accelerate biochemical reactions within living organisms without being consumed in the process (they can be used repeatedly in multiple reaction cycles without undergoing permanent changes themselves). This catalytic function is crucial for processes like digestion, metabolism, and DNA replication in organisms.
Biochemical reactions refer to the chemical processes that occur within living organisms to sustain life. These reactions involve the transformation of substrates into products through various pathways, and they are essential for cellular functions, growth, and maintenance.
It features Pepsin an enzyme that helps digest proteins, plus betaine hydrochloride to promote proper pH levels in the stomach. Together they make an excellent digestive team to help tackle protein problems.
- Provides hydrochloric acid to help maintain gastric pH
- Promotes healthy digestion, especially protein
- Supports overall nutrient absorption
- Provides additional acidity to the stomach
- Betaine HCL releases hydrochloric acid after swallowing, the same acid that is produced naturally by the stomach
- These tablets are designed to dissolve in the stomach where the acidity is required
- As we age our natural production of hydrochloric acid can decline, but its importance for the breakdown of food in the gut remains unchanged
Swanson w/ VegPeptase (iHerb)Lamberts w/ Pepsin
Stay on suggested use (max 2 capsules), huge doses of Betaine conflicts with Methylation.
Functions of Betaine HCl
- Digestive Support: Helps stimulate the production of hydrochloric acid in the stomach, improving digestion of proteins and absorption of nutrients.
- pH Regulation: Aids in maintaining the acidic environment of the stomach, which is essential for the proper functioning of digestive enzymes.
- Nutrient Absorption: Enhances the absorption of vital nutrients like vitamin B12, calcium, and magnesium.
Pepsin is an enzyme that plays a crucial role in the digestion of proteins. It is produced in the stomach of animals, including humans.
VegPeptase (a vegan-sourced pepsin) an enzyme that helps digest proteins.
VegPeptase is not extracted from fruits, instead, it is primarily produced through fermentation using certain strains of fungi or bacteria. While many enzymes can be extracted from fruits, VegPeptase specifically does not originate from this source.
Fruits may contain natural enzymes, such as bromelain from pineapples or papain from papayas, but VegPeptase derives from plant-based microbial processes rather than direct extraction from fruits.
Enzymes are specialized types of proteins that act as biological catalysts, speeding up chemical reactions in the body. While all enzymes are proteins, not all proteins are enzymes. Proteins serve a broader range of functions, including structural support, transport, and immune responses.
Biological catalysts are substances that accelerate biochemical reactions within living organisms without being consumed in the process (they can be used repeatedly in multiple reaction cycles without undergoing permanent changes themselves). This catalytic function is crucial for processes like digestion, metabolism, and DNA replication in organisms.
Biochemical reactions refer to the chemical processes that occur within living organisms to sustain life. These reactions involve the transformation of substrates into products through various pathways, and they are essential for cellular functions, growth, and maintenance.
Diosmectite is a naturally occurring clay mineral, specifically a smectite, derived from volcanic ash. when used as supplement creates a thin film on the epithelial intestinal cells. The film can facilitate the healing process of mucosal lesions by providing a suitable environment for recovery, but it can also influence nutrient absorption.
Simethicone is an over-the-counter medication commonly used to relieve symptoms of gas and bloating in the gastrointestinal tract.
Zarbis.Diaraney
Zarbis.Laxaney Tea - Senna leaves & Fennel
Zarbis.Senna Pods - Senna leaves
Zarbis.Laxaney Tabs - cassia angustifolia / aloe vera / sweet fennel
Simethicone is an over-the-counter medication commonly used to relieve symptoms of gas and bloating in the gastrointestinal tract.
Zarbis.Diaraney
Zarbis.Laxaney Tea - Senna leaves & Fennel
Zarbis.Senna Pods - Senna leaves
Zarbis.Laxaney Tabs - cassia angustifolia / aloe vera / sweet fennel
Deglycyrrhizinated licorice (DGL)
Is a licorice extract from the ayurvedic herb Glycyrrhiza glabra that has been shown to support GI mucosal health, promote healthy microbial environments, and potentially have anti-inflammatory and antioxidant properties. Natural Factors.DGL Chewable
GutGard® a patented ( by Indian company Natural Remedies [2] ) form of DGL.
source casi
GPT :
DGL is a form of licorice root that has had the glycyrrhizin compound removed, making it safer for long-term use. It is commonly used as a supplement to support gastrointestinal health, particularly by promoting the integrity of the gut lining.
Το GutGard® είναι ένα πατενταρισμένο, πλούσιο σε φλαβονοειδή εκχύλισμα από ρίζα γλυκόριζας (Glycyrrhiza glabra), ειδικά σχεδιασμένο για την υποστήριξη της υγείας του γαστρεντερικού συστήματος. Αποτελεί απογλυκυρριζινωμένο (deglycyrrhizinated) εκχύλισμα, γεγονός που μειώνει τις παρενέργειες, διατηρώντας παράλληλα υψηλά επίπεδα φλαβονοειδών (τουλάχιστον 10,5%) για μέγιστη αποτελεσματικότητα.
Studies on DGL
DGL vs GutGuard
2020 - Glycyrrhiza glabra (Licorice)
2011 - Alleviates Symptoms of Functional Dyspepsia
Is a licorice extract from the ayurvedic herb Glycyrrhiza glabra that has been shown to support GI mucosal health, promote healthy microbial environments, and potentially have anti-inflammatory and antioxidant properties. Natural Factors.DGL Chewable
GutGard® a patented ( by Indian company Natural Remedies [2] ) form of DGL.
Nutramins.GutGuard (contains 150mg)
source casi
GPT :
DGL is a form of licorice root that has had the glycyrrhizin compound removed, making it safer for long-term use. It is commonly used as a supplement to support gastrointestinal health, particularly by promoting the integrity of the gut lining.
Το GutGard® είναι ένα πατενταρισμένο, πλούσιο σε φλαβονοειδή εκχύλισμα από ρίζα γλυκόριζας (Glycyrrhiza glabra), ειδικά σχεδιασμένο για την υποστήριξη της υγείας του γαστρεντερικού συστήματος. Αποτελεί απογλυκυρριζινωμένο (deglycyrrhizinated) εκχύλισμα, γεγονός που μειώνει τις παρενέργειες, διατηρώντας παράλληλα υψηλά επίπεδα φλαβονοειδών (τουλάχιστον 10,5%) για μέγιστη αποτελεσματικότητα.
Studies on DGL
| Year | Study Focus | Findings |
|---|---|---|
1978 | Treatment of gastric ulcers | A controlled trial indicated positive clinical outcomes in patients treated with DGL. |
2002 | Efficacy in functional dyspepsia | Showed significant improvement in gastrointestinal symptoms when using DGL. |
2022 | Promotion of gastric mucosal health | Studies indicated that DGL supports gut integrity and microbial health. |
2025 | Clinical trial on GutGard (a DGL product) for various gastric issues | Demonstrated efficacy in alleviating symptoms of functional dyspepsia and showed antiulcer activity. |
2025 | Phase III trial on DGL for Gastroesophageal Reflux Disease (GERD) | Reported significant symptom relief in participants with GERD. |
DGL vs GutGuard
| Feature | DGL | GutGuard |
|---|---|---|
| Composition | Pure extract of deglycyrrhizinated licorice, focusing on mucosal protection. | Contains a proprietary blend including DGL, aloe vera, and other ingredients designed for gut health. |
| Mechanism of Action | Stimulates mucus production, provides a protective barrier, anti-inflammatory. | Multi-faceted approach with DGL for mucosal support, along with aloe for soothing and additional herbs for digestive balance. |
| Primary Benefits | Eases symptoms of ulcers, GERD, and IBS. | Addresses a broader range of digestive issues and supports overall gut health. |
| Research and Evidence | Established history with numerous studies showing benefits for gastric health. | Newer product with promising but less established research; effectiveness may depend on individual components. |
| Usage | Typically taken in standard doses (300-1000 mg) before meals. | Dosing varies based on the formulation; generally recommended before meals as well (aka total 2x75mg). |
| Safety Profile | Generally safe; lacks side effects associated with standard licorice. | Safety varies by formulation; generally considered safe but should still be discussed with a healthcare provider. |
2020 - Glycyrrhiza glabra (Licorice)
2011 - Alleviates Symptoms of Functional Dyspepsia