Have gone new ways to find enzymes that can remove both the A and B blood antigens and the sugars that block them. The research teams discovered new mixtures of enzymes from the human gut bacterium Akkermansia muciniphila that feeds by breaking down the mucus, which covers the surface of the gut. It turns out that these enzymes are exceptionally efficient, as the complex sugars at the surface of the intestinal mucosa share chemical resemblance with those found at the surface of blood cells.
https://www.dtu.dk/english/newsarchive/2024/04/enzymes-open-new-path-to-universal-donor-blood
https://www.dtu.dk/english/newsarchive/2024/04/enzymes-open-new-path-to-universal-donor-blood