Acute exposures to IQOS aerosol impairs FMD in rats. IQOS use does not necessarily avoid the adverse cardiovascular effects of smoking cigarettes.
https://tobacco.ucsf.edu/more-evidence-pmi-iqos-bad-cigarette-vascular-endothelial-function-impaired-aerosol-single-iqos-heatstick-same-extent-cigarette-smoke